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Revealing interior temperature of Antarctic ice sheet

As ESA’s SMOS satellite celebrates 10 years in orbit, yet another result has been added to its list of successes. This remarkable satellite mission has shown that it can be used to measure how the temperature of the Antarctic ice sheet changes with depth - and it’s much warmer deep down.

CCREEE appoints Executive Director

(CARICOM Secretariat, Turkeyen, Greater Georgetown, Guyana) The Caribbean Centre for Renewable Energy and Energy Efficiency (CCREEE) has appointed Dr Gary Jackson as its Executive Director.

Blossom Cottage recalls its Morello Cherry Cordial due to fermentation in the bottle

Feeding the World International Ltd trading as Get Stuffed recalls a variety of its Delicious Indian Cuisine on the Go products due to incorrect shelf life labelling

HERSCHEL CLOSES ITS EYES ON THE UNIVERSE

March of the motes

An unseen silicon army is gathering information on Earth and its inhabitants. It’s not an alien reconnaissance mission: smart dust is finally hitting the streets, says Anil Ananthaswamy

PlayStation data theft hits 77m gamers

Sony has warned users of its PlayStation Network that their personal information, including credit card details, may have been stolen.

State aid: Commission adopts guidance on training aid and aid to disadvantaged and disabled workers

The European Commission has adopted two guidance papers setting out criteria for the in-depth assessment of large amounts of training aid and of aid to disadvantaged and disabled workers. The guidance outlines the kind of information required by the Commission for its assessment and the assessment methodology, which is based on the balancing of the positive and negative effects of the aid. The criteria are in line with the Commission's refined economic approach in state aid analysis, based on the principles set out in the State Aid Action Plan (see IP/05/680 and MEMO/05/195 ). They are part of the Commission's efforts to clarify and simplify state aid rules.

Broadband : Commission consults on regulatory strategy to promote very high speed Internet

T he European Commission has launched a public consultation on its revised proposals for the regulation of Next Generation Access (NGA) broadband networks, in the form of a draft Commission Recommendation. A previous public consultation held during the last quarter of 2008 confirmed general support for the objective of the Commission to achieve a common regulatory framework for NGA in order to foster timely investment in very high speed networks while ensuring that the competitive structure of the market is maintained. In the light of comments from stakeholders, the revised draft Recommendation includes mechanisms to allocate the investment risk between investors and operators seeking access to NGA networks. The draft Recommendation forms part of the European Broadband Strategy that the March European Council invited the Commission to develop by the end of 2009. The public consultation will be open until 24 July 2009. The Commission plans to adopt the Recommendation, taking account of comments received, before the end of 2009.

Apple, AT&T sued for over-saturating 3G network with iPhones

A San Diego-based lawsuit filed late last week alleges that Apple and its carrier partner AT&T have knowingly oversold iPhone 3G, promising fast speeds only to see a glut of customers bog down the network with devices that themselves are flawed.

Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Resp

Silencing of Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Responsive Cancer Cells.Sabrina Rotolo 1, Simona Ceccarelli 1, Ferdinando Romano 1, Luigi Frati 1,2, Cinzia Marchese 1, Antonio Angeloni 1* 1 Dipartimento di Medicina Sperimentale, Universita` Sapienza di Roma, Roma, Italy, 2 Istituto Neurologico Mediterraneo ‘‘Neuromed, Pozzilli, ItalyAbstract : BackgroundKeratinocyte growth factor receptor (KGFR) is a splice variant of the FGFR2 gene expressed in epithelial cells. Activation of KGFR is a key factor in the regulation of physiological processes in epithelial cells such as proliferation, differentiation and wound healing. Alterations of KGFR signaling have been linked to the pathogenesis of different epithelial tumors. It has been also hypothesized that its specific ligand, KGF, might contribute to the development of resistance to 5-fluorouracil (5-FU) in epithelial cancers and tamoxifen in estrogen-positive breast cancers.Abstract : Methodology/Principal FindingsSmall interfering RNA was transfected into a human keratinocyte cell line (HaCaT), a breast cancer derived cell line (MCF-7) and a keratinocyte primary culture (KCs) to induce selective downregulation of KGFR expression. A strong and highly specific reduction of KGFR expression was observed at both RNA (reduction = 75.7%, P = 0.009) and protein level. KGFR silenced cells showed a reduced responsiveness to KGF treatment as assessed by measuring proliferation rate (14.2% versus 39.0% of the control cells, P

Olig2 Induction and Its Implications for Neuronal Repair

Fate Determinant Expression in the Lesioned Brain