Cerca Articoli

Trovati 632 risultati per "Erasmus and International Home" (Pagina 1 di 53) 4360.61ms • aggiornato
The Commission proposes concrete action for sustainable development and a fairer world

The Commission proposes concrete action for sustainable development and a fairer world

How should we be tackling the problem of poverty? What is the best way of managing our natural resources and the environment? How should we finance development? With an eye to the forthcoming major international events at which these and other questions will be discussed the Monterrey Conference on development financing (March 2002), the World Summit for sustainable development (in September 2002), and the practical application of the Doha development agenda of November 2001, the European Commission is proposing a first set of responses, making a forceful case for multilateralism as the only effective way of addressing these global challenges. The three communications which the Commission today adopted, at the initiative of President Romano Prodi, the Member of the Commission responsible for economic and monetary affairs, Pedro Solbes and the Member responsible for development and humanitarian aid, Poul Nielson, will be widely discussed within civil society and by the public at large.

European Union European_union 11 Mar 2002
178.7K 0
Pubblicati i bandi Erasmus Plus SMS e Overworld “Overseas Student Exchange” a.a. 2021-2022

Pubblicati i bandi Erasmus Plus SMS e Overworld “Overseas Student Exchange” a.a. 2021-2022

PUBBLICATI I BANDI ERASMUS PLUS SMS E OVERWORLD “OVERSEAS STUDENT EXCHANGE” A.A. 2021-2022 Disponibili online le modalità per partecipare alle iniziative per trascorrere periodi di studio presso Università Europee partner dell’Ateneo di Parma e presso Università extraeuropee con un protocollo di collaborazione culturale e scientifica con il nostro Ateneo. Scadenza domande: 19 febbraio 2021

UNIPR Università degli studi di Parma Education 24 Jan 2021
13.8K 0
Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast

Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast

• Otx2 binds to the promoter/enhancer region of Oct4, Sox2, and Nanog in ESCs and EpiSCs • Otx2 binding to the Nanog promoter helps maintain the integrity of ESC compartments • Loss of this Otx2-binding site induces primed-like features in ESCs • Otx2 regulation of Nanog contributes to ICM differentiation of the epiblast Mouse embryonic stem cells (ESCs) and the inner cell mass (ICM)-derived epiblast exhibit naive pluripotency. ESC-derived epiblast stem cells (EpiSCs) and the postimplantation epiblast exhibit primed pluripotency. Although core pluripotency factors are well-characterized, additional regulators, including Otx2, recently have been shown to function during the transition from naive to primed pluripotency. Here we uncover a role for Otx2 in the control of the naive pluripotent state. We analyzed Otx2-binding activity in ESCs and EpiSCs and identified Nanog, Oct4, and Sox2 as direct targets. To unravel the Otx2 transcriptional network, we targeted the strongest Otx2-binding site in the Nanog promoter, finding that this site modulates the size of specific ESC-subtype compartments in cultured cells and promotes Nanog expression in vivo, predisposing ICM differentiation to epiblast. Otx2-mediated Nanog regulation thus contributes to the integrity of the ESC state and cell lineage specification in preimplantation development.

CNR Science 22 Jun 2016
179.2K 0
Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Resp

Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Resp

Silencing of Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Responsive Cancer Cells.Sabrina Rotolo 1, Simona Ceccarelli 1, Ferdinando Romano 1, Luigi Frati 1,2, Cinzia Marchese 1, Antonio Angeloni 1* 1 Dipartimento di Medicina Sperimentale, Universita` Sapienza di Roma, Roma, Italy, 2 Istituto Neurologico Mediterraneo ‘‘Neuromed, Pozzilli, ItalyAbstract : BackgroundKeratinocyte growth factor receptor (KGFR) is a splice variant of the FGFR2 gene expressed in epithelial cells. Activation of KGFR is a key factor in the regulation of physiological processes in epithelial cells such as proliferation, differentiation and wound healing. Alterations of KGFR signaling have been linked to the pathogenesis of different epithelial tumors. It has been also hypothesized that its specific ligand, KGF, might contribute to the development of resistance to 5-fluorouracil (5-FU) in epithelial cancers and tamoxifen in estrogen-positive breast cancers.Abstract : Methodology/Principal FindingsSmall interfering RNA was transfected into a human keratinocyte cell line (HaCaT), a breast cancer derived cell line (MCF-7) and a keratinocyte primary culture (KCs) to induce selective downregulation of KGFR expression. A strong and highly specific reduction of KGFR expression was observed at both RNA (reduction = 75.7%, P = 0.009) and protein level. KGFR silenced cells showed a reduced responsiveness to KGF treatment as assessed by measuring proliferation rate (14.2% versus 39.0% of the control cells, P

Redazione Health 03 Jul 2008
180.0K 0
FOOD AND INDUSTRIAL MICROBIOLOGY

FOOD AND INDUSTRIAL MICROBIOLOGY

Food spoilage, food infections and intoxications caused by microorganisms and methods for their detection Dr. Neeraj Dilbaghi. Reader, Department of Bio & Nano Technology. Guru Jambheshwar University of Science and Technology Hisar- 125001 and Dr (Mrs.) S. Sharma. Professor, Department of Microbiology, CCS Haryana Agricultural University, Hisar- 125001 (Revised 25-Sep-2007) IntroductionFood Spoilage and General Principles Underlying Spoilage of Food Intrinsic Parameters Extrinsic Parameters Microbial Spoilage of Foods Spoilage of fresh and ready-to-eat meat products Spoilage of milk and milk products Spoilage of fruits and vegetables Spoilage of canned foods Major Food Borne Infections/ Intoxications Caused by Bacteria General Control Measures for Prevention of Food Borne Diseases Microbial Testing of Foods Conventional MethodsRapid Detection of Emerging High Risk Pathogens in Foods

Redazione Alimentation 23 Dec 2018
21.3K 0
State aid: Commission adopts guidance on training aid and aid to disadvantaged and disabled workers

State aid: Commission adopts guidance on training aid and aid to disadvantaged and disabled workers

The European Commission has adopted two guidance papers setting out criteria for the in-depth assessment of large amounts of training aid and of aid to disadvantaged and disabled workers. The guidance outlines the kind of information required by the Commission for its assessment and the assessment methodology, which is based on the balancing of the positive and negative effects of the aid. The criteria are in line with the Commission's refined economic approach in state aid analysis, based on the principles set out in the State Aid Action Plan (see IP/05/680 and MEMO/05/195 ). They are part of the Commission's efforts to clarify and simplify state aid rules.

Redazione Health 23 Jun 2009
314.0K 0
NASA Orders Second Boeing Crew Mission to International Space Station

NASA Orders Second Boeing Crew Mission to International Space Station

Engineers from NASA’s Langley Research Center in Hampton, Virginia, and Boeing dropped a full-scale test article of the company’s CST-100 Starliner into Langley’s 20-foot-deep Hydro Impact Basin. Although the spacecraft is designed to land on land, Boeing is testing the Starliner’s systems in water to ensure astronaut safety in the unlikely event of an emergency during launch or ascent. Testing allows engineers to understand the performance of the spacecraft when it hits the water, how it will right itself and how to handle rescue and recovery operations. The test is part of the qualification phase of testing and evaluation for the Starliner system to ensure it is ready to carry astronauts to and from the International Space Station.

Agenzia spaziale Europea Science 17 Feb 2016
21.4K 0
Pagina 1 di 53 Successiva