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Pat Mooney was interviewed by Maria Heibel
Pat Mooney has more than four decades experience working in international civil society, first addressing aid and development issues and then focusing on food, agriculture and commodity trade. Mooney’s more recent work has focused on geoengineering, nanotechnology, synthetic biology and global governance of these technologies as well as corporate involvement in their development. The author or co-author of several books on the politics of biotechnology and biodiversity, Pat Mooney received The Right Livelihood Award (the “Alternative Nobel Prize“) in the Swedish Parliament in 1985. In 1998 Mooney received the Pearson Medal of Peace from Canada’s Governor General. He also received the American “Giraffe Award“ given to people “who stick their necks out“. Pat Mooney has no university training, but is widely regarded as an authority on agricultural biodiversity and new technology issues.
THE FANCONI ANAEMIA/BRCA PATHWAY
Fanconi anaemia (FA) is a rare genetic cancer-susceptibility syndrome that is characterized by congenital abnormalities, bone-marrow failure and cellular sensitivity to DNA crosslinking agents. Seven FA-associated genes have recently been cloned, and their products were found to interact with well-known DNA-damage-response proteins, including BRCA1, ATM and NBS1. The FA proteins could therefore be involved in the cell-cycle checkpoint and DNA-repair pathways. Recent studies implicate the FA proteins in the process of repairing chromosome defects that occur during homologous recombination, and disruption of the FA genes results in chromosome instability ”€ a common feature of many human cancers.